Vitamin D Deficiency at Melanoma Diagnosis Is Associated with Higher Breslow Thickness
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Vitamin D Deficiency at Melanoma Diagnosis Is Associated with Higher Breslow Thickness
BACKGROUND Epidemiological evidence shows that people with thicker, or higher stage, melanomas have lower vitamin D status compared to those with thinner tumours. Evidence from experimental studies is inconsistent, but some suggest that administration of vitamin D metabolites can decrease tumour aggressiveness. OBJECTIVES Determine the relationship between vitamin D status at diagnosis and me...
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THP-1 cells but appeared in response to TNF alpha (4.96 1 0.59 pg/mL). Both manumycin (0.34 1 0.48 pg/mL) and asukamycin (1.06 1 0.81) inhibited IL-1 beta release induced by TNF alpha. IL-18 was found to be constitutively produced (14.68 1 7.83 pg/mL) and the release was doubled by TNF alpha (30.98 1 2.21 pg/mL) and inhibited to basal values by both manumycin (18.04 1 10.21 pg/mL) and asukamyci...
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ژورنال
عنوان ژورنال: PLOS ONE
سال: 2015
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0126394